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| Jeff Gross | |
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Assistant Professor Ph.D. Duke University Office Patterson
203 Gross Lab home page |
| Video PC Mac | |
| My laboratory is interested in vertebrate eye development and visual system function. For our studies we employ the zebrafish, Danio rerio, as a model system. Combining forward genetic screens with reverse genetic and embryological manipulations we hope to understand the molecular, cellular and developmental events that regulate eye formation. Current areas of interest in the lab are the development and maintenance of the lens and retinal pigment epithelium, the molecular and cellular mechanisms regulating ocular morphogenesis and the patterning events that generate positional asymmetries within the retina along the dorsal-ventral and nasal-temporal axes. Our research combines molecular, cellular, biochemical, transgenic and in vivo imaging techniques to address these questions. It is our hope that these studies will ultimately lead to a better understanding of pathogenic disorders of the eye such as macular degeneration, cataracts and ocular coloboma that often result in blindness for afflicted patients. | |
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