The University of Texas at Austin
 
About Bio Sci Calendar Directory Facilities Maps Organizations Research Units Support Services Online Store Contact Us

Directory  

 back

Faculty
Janice Fischer
Professor in Molecular Cell & Developmental Biology

Email: jaf@mail.utexas.edu
Website
Main Office: MBB 1.312AA
Phone: 471-5831

Alternate Office: MBB 1.312A & B
Alt. Phone: 471-2826

Mailing Address
The University of Texas at Austin - ICMB
1 University Station A4800
2500 Speedway
Austin ,TX 78712-1095
Janice Fischer

Research Summary

My laboratory uses Drosophila genetics and molecular biology to study universal mechanisms of development. We do most of our experiments with the Drosophila compound eye. Patterning of the Drosophila compound eye involves nearly every known cell signaling pathway and the eye affords many experimental advantages. We are studying how cell-cell interactions are regulated by membrane trafficking and ubiquitin. Also, are using a Drosophila model to understand Angelman syndrome, a human neurological disease caused by loss of function of a gene called UBE3A. UBE3A encodes a specificity factor for ubiquitination. We are using Drosophila genetics to understand the function of UBE3A and the biochemical effects of its loss relevant to Angelman syndrome.