The University of Texas at Austin
 

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Faculty
Scott Stevens
Associate Professor of Molecular Genetics & Microbiology, Chair of Graduate Studies Committee

Email: scott.stevens@austin.utexas.edu
Website
Main Office: NMS 1.122
Phone: (512) 232-9303

Alternate Office: NMS 1.262
Alt. Phone: (512) 232-9377

Mailing Address
The University of Texas at Austin
Section of Molecular Genetics and Microbiology
2506 Speedway Stop A5000
Austin ,TX 78712-1191
Scott Stevens

Research Summary

Ribonucleoproteins (RNPs) function in many cellular processes and the malfunction of some of these RNPs cause serious human disease. To better understand how disease states can be corrected, our laboratory studies the ways in which RNA and protein assemble into large RNP complexes, how those complexes function, how they are rearranged in the course of their action and how they get put back together again. Using yeast genetics, biochemistry, cryo-electron microscopy and X-ray crystallography, we seek to understand the details of the structure and function of the yeast spliceosome and other RNPs. We are also experimenting in the mammalian system by designing human cells and mice to allow us to study the complex splicing reaction in these model systems as well.