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Faculty
Somshuvra (Som) Mukhopadhyay
Assistant Professor

Email: som@austin.utexas.edu
Website
Main Office: BME 3.510F
Phone: 232-8200

Alternate Office: BME 5.514
Alt. Phone: 471-5873

Mailing Address
3.510F BME
107 W. Dean Keeton
Austin ,TX 78712

Somshuvra (Som) Mukhopadhyay


Research Summary

We study intracellular membrane trafficking in the context of normal cell physiology and human disease. Transport of proteins and lipids between membrane bound subcellular organelles is essential for life. Cellular events dependent on trafficking include fundamental processes such as biosynthetic secretion, receptor-mediated endocytosis, synaptic transmission, and ion homeostasis. Alterations in trafficking can have devastating consequences, and several incurable human diseases such as cystic fibrosis, Alzheimer's disease, Huntington's disease and Wilson's disease occur due to defects in trafficking. We are interested in understanding how membrane trafficking regulates physiologically relevant cellular processes and how defects in trafficking alter cell physiology to induce human disease. Current projects in the lab focus on: 1. Studying the role of trafficking in metal homeostasis and induced neurotoxicity; 2. Elucidating the mechanisms mediating intracellular transport of Shiga and other bacterial toxins. Please view our lab website to read more about our research, publications, and available positions.

 

 

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