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Mark A. Kirkpatrick

Kirkpatrick, Mark A.
Professor

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Main Office: PAT 652 Phone: (512) 471-5996

Alternate Office: PAT 648 Phone: (512) 471-3760

Mailing Address:
The University of Texas at Austin
Section of Integrative Biology
1 University Station C0930
Austin,Texas 78712


Research Summary:
How does evolution generate the fantastic diversity we see in nature? Our lab studies this question from a genetic perspective. My work uses mathematical models and develops statistical tools to test hypotheses. Students and postdocs in our group compliment these theoretical approaches with experimental ones. What kinds of questions interest us? We work on a wide range of problems. A big focus is chromosome evolution. Despite huge advances in genomic science, we still have very little understanding of such basic questions as: Why do species have different numbers of chromosomes?, How and why do chromosome rearrangements evolve?, and Why do some taxa keep re-evolving new sex chromosomes? Our results suggest that adaptation to local ecological conditions and sexually antagonistic selection are important drivers of chromosome evolution. Other topics that we work on include: • Speciation. We study how and why reproductive isolation evolves. In one recent study, we determined when selection against hybrids will (and will not) finish off the process of speciation.. • Sexual selection. We are interested in how female mating preferences evolve, and how do they affect male traits. One hot topic is intransitive mating preferences. • Species ranges. A basic mystery is why species don’t always expand their geographical ranges by adapting to more extreme conditions. We are developing models that show how gene flow, genetic constraints, and biological interactions can limit geographical ranges. The results may have useful applications in conservation biology. What do graduate students and postdocs in our lab work on? I typically collaborate with people in the lab on one or more projects, but I also encourage independent research on topics that I do not work on. I also strongly support collaborations within our group, and collaborations with researchers in other labs at UT and abroad.



Publications:
2010 Hill WG, Kirkpatrick M, What has animal breeding taught us about evolution?, Annual Review of Ecology, Evolution, and Systematics 41: 1-20
2007 van Doorn GS, Kirkpatrick M, Turnover of sex chromosomes induced by sexual conflict, Nature 449: 909-912
2006 Kirkpatrick M, Barton N, Chromosome inversions, local adaptation, and speciation, Genetics 173: 419-434