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| Steven A. Vokes | |
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Assistant Professor Ph.D. University of Texas at Austin Office MBB 1.436 |
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| Our major research interest lies in understanding the transcriptional and cis-regulatory mechanisms underlying cellular specification during the process of embryonic development. We employ a combination of genetic, molecular and genomic approaches using the mouse limb bud as a model system.
Our current efforts are focused on two major questions: -What are the critical cis-regulatory interactions necessary for generating dynamic gene expression patterns during development? -How are multiple signaling pathways integrated on the transcriptional level?" |
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2007 Vokes, S.A., Ji, H., McCuine, S., Tenzen, T., Giles, S., Zhong, S., Longabaugh, W.J.R., Davidson, E.H., Wong, W.H., and McMahon, A.P, Genomic Characterization of Gli-Activator Targets in Sonic Hedgehog-Mediated Neural Patterning, Development 134:1977-1989. 2006 Ji, H., Vokes, S.A. and Wong, W.H. , A comparative analysis of genome-wide chromatin immunoprecipitation data for mammalian transcription factors, Nucleic Acids Res. 34:e146. 2005 Nybakken, K., Vokes, S.A., Lin, T.Y., McMahon, A.P. and Perrimon, N. , A genome-wide RNA interference screen in Drosophila cells for novel components of the Hh signaling pathway, Nature Genetics 37:1323-1332. 2004 Vokes, S.A., Yatskievych, T.A., Heimark, R.L., McMahon, J., McMahon, A.P., Antin, P.B. and P.A. Krieg , Hedgehog signaling is essential for endothelial tube formation during vasculogenesis, Development 146:4371-4380. |
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