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Some Recent Publications from the Zakon Lab


Hormonal Regulation of Ion Channels

Markham MR, McAnelly ML, Stoddard PK, Zakon HH (2009)  Circadian and Social Cues Regulate Ion Channel Trafficking PLoS Biol 7(9): e1000203.

McAnelly ML, Zakon HH (2000) Co-regulation of voltage-dependent kinetics of Na+ and K+ currents. J. Neuroscience 20: 3408-3414.

McAnelly ML, Silva A. Zakon HH (2003) Cyclic AMP modulates electrical signaling in a weakly electric fish. J. Comp. Physiol. A 189: 273-282.

Stoddard PK , Zakon HH, Markham MR, McAnelly ML (2006) Regulation and modulation of electric waveforms in gymnotiform electric fish. J. Comp. Physiol. A 153: 477-487.

Few WP, Zakon HH (2007) Sex differences in and hormonal regulation of Kv1
potassium channel gene expression in the electric organ: molecular control of a social signal. Developmental Neurobiology 67: 535-549.

Liu H, Wu M-M, Zakon HH (2007) Individual variation and hormonal modulation of a sodium channel b subunit in the electric organ correlates with variation in a social signal. Developmental Neurobiology 67(10): 1289-1304.

McAnelly ML, Zakon HH (2007) Androgen modulates the kinetics of the delayed rectifying K+ current in the electric organ of a weakly electric fish. Developmental Neurobiology 67(12): 1589-1597.

Molecular Evolution of Ion Channels

Lopreato G, Lu Y, Southwell A, Atkinson N, Hillis DM, Wilcox T, Zakon, HH (2001) Evolution and divergence of Na+ channel genes in vertebrates. Proceedings of the National Academy of Sciences USA 98: 7588-7592.

Zakon HH, Lu Y, Zwickl DJ, Hillis DM (2006) Sodium channel genes and the evolution of diversity in communication signals of electric fishes: convergent molecular evolution. Proceedings of the National Academy of Sciences USA 103: 3675-3680.

Novak AE, Jost MC, Lu Y, Taylor AD, Zakon HH, Ribera AB (2006) Gene duplications and evolution of vertebrate voltage-gated sodium channels. J. Molecular Evolution 63: 208 - 221.

Jost MC, Hillis DM, Lu Y, Kyle JW, Fozzard HA, Zakon HH (2008) Toxin-resistant sodium channels: Parallel adaptive evolution across a complete gene family. Molecular Biology & Evolution (in press).

Long-term Plasticity of Ion Channels

Oestreich J, Zakon HH (2002) The long-term resetting of a brainstem pacemaker nucleus by synaptic input: a model for sensorimotor adaptation. J. Neurosci. 22(18): 8287-8296.

Oestreich J, Zakon HH (2005) Species-specific differences in sensorimotor adaptation are correlated with differences in social structure. J. Comp. Physiol A 191(9): 845-856.

Oestreich J, Dembrow N, George A, Zakon HH (2006) A "sample-and hold" pulse-counting integrator as a mechanism for graded memory underlying sensorimotor adaptation. Neuron 49: 577-588.

Development & Evolution of Electric Organ

Unguez GA, Zakon HH (2002) Skeletal muscle transformation into electric organ in S. macrurus depends on innervation. J. Neurobiology 53: 391-402.

Hormones & Behavior

Few, WP, Zakon, HH (2001) Local action of androgens and androgen receptor expression in the electric organ of a weakly electric fish. Hormones & Behavior, 40: 434-442.

Triefenbach, FA, Zakon HH (2002) Signaling responses to sexual and reproductive status cues in the weakly electric fish, Apteronotus leptorhynchus. Animal Behaviour 65: 19-28.

Tallarovic, SK and Zakon, HH (2002) Electrocommunication signals in female brown ghost electric knifefish, Apteronotus leptorhynchus. J Comp Physiol A 188: 649-657.

Tallarovic, S and Zakon, HH (2005) Electric organ discharge frequency jamming during social interactions in brown ghost knifefish, Apteronotus leptorhynchus. Animal Behavior 70: 1355-1365.

Triefenbach, F, Zakon, HH (2008) Changes in signaling during agonistic interactions between male weakly electric knifefish, Apteronotus leptorhynchus. Animal Behavior (in press).

Recent Reviews

Zakon HH (2002) Convergence on the molecular level. Brain, Behavior and Evolution. 59: 250-261.

Zakon HH (2003) Insights into the mechanisms of neuronal processing from electric fish. Current Opinions in Neurobiology 13: 744-750.