Professor in Pharmacy
Main Office: PHR 5.224B
Alt. Phone: 471-1018
The University of Texas at Austin - ICMB
1 University Station A1915
2409 University Ave.
Austin ,TX 78712-1095
Research SummaryMy primary research interests center upon the interactions between excitatory and inhibitory neurotransmitters and their synaptic and cellular effects that regulate certain aspects of normal neural function as well as some neuropathologies. We are particularly focused upon the synaptic changes that contribute to the induction and expression of alcohol-related disorders (withdrawal, dependence, tolerance, toxicity, cognitive
effects), but we also work on other processes such as learning and memory, neuronal development and the development
of epilepsy. My lab is composed of three main units: (1) an electrophysiology core which includes patch clamp recordings in brain slices, dissociated cultures or organotypic explants; (2) a molecular core which uses immunoblot, immunofluorescence,
pcr, and gene transfer techniques, and (3) an imaging core which houses laser scanning confocal and two-photon microscopes. Therefore, students have access to a broad range of some of the most advanced techniques in use in neurobiology today.